Target Protein: GLUT4
Immunogen Range: 467-509/509
Entrez Gene: 6517
Swiss Prot: P14672
Source: KLH conjugated synthetic peptide derived from human GLUT4
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Background: GLUT4 is the facilitated glucose transporter expressed exclusively in adipocytes and muscle cells, and is also known as the "insulin-responsive" glucose transporter. GLUT4 translocates from an ill-defined intracellular compartment to the plasma membrane in response to insulin. The total cellular content of GLUT4 is significantly decreased in adipose cells from many patients with Type II diabetes mellitus, and animals with some types of experimental diabetes.
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.